Gout Explained
- janlindquist
- Dec 28, 2025
- 3 min read
Gout is a systemic issue rooted in metabolic dysfunction, inflammation, and poor gut health, caused from eating a diet high in carbohydrates, processed foods and alcohol. You can get gout [buildup of uric acid in the blood] in any joint, but it most commonly begins in the big toe and frequently affects the ankles, knees, fingers, wrists and elbows. Gout is very painful and another warning sign to take our dietary choices seriously.

Wrong Direction.
For decades, red meat has been blamed for gout - but biology tells a very different story.
Gout isn't driven by eating nourishing protein. It's driven by insulin resistance, sugar, and fructose overload.
Real Science.
Sugar and fructose raise uric acid production.
Insulin resistance reduces uric acid excretion by the kidneys.
Chronic inflammation allows uric acid excretion by the kidneys.
Chronic inflammation allows crystals to form in joints.
Eating Red Meat:
does not spike insulin.
supports satiety & stable blood sugar.
does not impair uric acid clearance when insulin sensitivity is intact.
Studies consistently show that sugary drinks and ultra-processed foods raise gout risk far more than whole animal foods.
What is Gout?
Gout is caused by the accumulation of uric acid crystals in joints. Uric acid itself is a normal metabolic by-product, formed when the body breaks down purines.
Purines come from:
Our own cells [the majority]
Normal tissue turnover
Some foods
What we should be asking instead:
Why uric acid accumulates instead of being cleared?
Insulin resistance and impaired kidney handling of uric acid is why gout occurs.
Insulin Resistance Role in Gout.
Insulin directly affects how the kidneys excrete uric acid.
When insulin resistance levels are chronically high, the kidneys reabsorb uric acid instead of excreting it.
Blood uric acid rises.
Crystal formation becomes more likely.
This explains why gout clusters strongly with:
Obesity
Type 2 diabetes
Fatty liver disease
Hypertension
All of these conditions are driven by insulin resistance, not red meat.
The best line of defence is to lower insulin through dietary changes, which will improve uric acid clearance.
Why Sugar & Fructose Matter More Than Meat
Fructose is primarily the sugar in fruits which our body can metabolize well.
Unfortunately, fructose is also found as high-fructose corn syrup [HFCS] in sodas, candy, and many condiments.
This is where we need to use caution, as fructose is uniquely harmful in gout because it:
Rapidly increases uric acid production.
Depletes ATP in liver cells.
Drives oxidative stress and inflammation.
Worsens insulin resistance.
Studies consistently show that sugary drinks, alcohol, [especially beer] and high fructose corn syrup intake strongly increases gout risk far greater than meat intake.
When the standard recommendation to address gout includes limiting red meat, it's often replaced with more refined carbohydrates, sugar, processed low-fat foods, and fructose-rich alternatives.
This worsens insulin resistance - the very condition driving gout.
A Warning Light.
Gout is a metabolic warning light, not a meat intolerance issue and the goal should be to:
Restore insulin sensitivity.
Reduce fructose foods and sugar load.
Improve mitochrondrial function.
Support kidney clearance.
Lower oxidative stress.
Eating red meat as a whole unprocessed food, fits naturally into a supportive metabolic health- improvement diet.
Blaming meat distracts us from the real problem - insulin resistance, and this delays true healing.
When we fix our metabolism through eating a whole, real food diet that reduces sugar and fructose - gout risk falls naturally.
Let's stop fearing real food and begin to fear the metabolic chaos that continuing to eat the Standard American Diet [SAD] is doing to us. Ultra-processed foods are low in fiber, low in healthy fats, and low in protein - exactly what our body really needs to flourish.
We are NOT broken, but under-nourished in the foods we NEED to be eating.
Correct the inputs and our body will heal.
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Thanks for reading,
Jan`




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